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Sodium cellulose sulfate: A promising biomaterial used for microcarriers’ designing

Qing-Xi Wu, Yi-Xin Guan, Shan-Jing Yao

Frontiers of Chemical Science and Engineering 2019, Volume 13, Issue 1,   Pages 46-58 doi: 10.1007/s11705-018-1723-x

Abstract: Due to a worldwide focus on sustainable materials for human health and economy services, more and more natural renewable biomass are regarded as promising materials that could replace synthetic polymers and reduce global dependence on petroleum resources. Cellulose is known as the most abundant renewable polymer in nature, varieties of cellulose-based products have been developed and have gained growing interest in recent years. In this review, a kind of water-soluble cellulose derivative, i.e., sodium cellulose sulfate (NaCS) is introduced. Details about NaCS’s physicochemical properties like solubility, biocompatibility, biodegradability, degree of substitution, etc. are systematically elaborated. And promising applications of NaCS used as biomaterials for microcarriers’ designing, such as micro-cell-carriers, micro-drug-carriers, etc., are presented.

Keywords： sodium cellulose sulfate     biomaterial     physicochemical properties     microcarriers    

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Combination of biomaterial transplantation and genetic enhancement of intrinsic growth capacities to

Bin Yu, Xiaosong Gu

Frontiers of Medicine 2019, Volume 13, Issue 2,   Pages 131-137 doi: 10.1007/s11684-018-0642-z

Abstract: To circumvent these barriers, biomaterial scaffolds are applied to bridge the lesion gaps for the regrowingGiven the complex pathophysiology of SCI, combining biomaterial scaffolds and genetic manipulation may

Keywords： spinal cord injury     biomaterial     extrinsic barrier     intrinsic regeneration capacity    

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Fabrication of scaffolds in tissue engineering: A review

Peng ZHAO, Haibing GU, Haoyang MI, Chengchen RAO, Jianzhong FU, Lih-sheng TURNG

Frontiers of Mechanical Engineering 2018, Volume 13, Issue 1,   Pages 107-119 doi: 10.1007/s11465-018-0496-8

Abstract:

Tissue engineering (TE) is an integrated discipline that involves engineering and natural science in the development of biological materials to replace, repair, and improve the function of diseased or missing tissues. Traditional medical and surgical treatments have been reported to have side effects on patients caused by organ necrosis and tissue loss. However, engineered tissues and organs provide a new way to cure specific diseases. Scaffold fabrication is an important step in the TE process. This paper summarizes and reviews the widely used scaffold fabrication methods, including conventional methods, electrospinning, three-dimensional printing, and a combination of molding techniques. Furthermore, the differences among the properties of tissues, such as pore size and distribution, porosity, structure, and mechanical properties, are elucidated and critically reviewed. Some studies that combine two or more methods are also reviewed. Finally, this paper provides some guidance and suggestions for the future of scaffold fabrication.

Keywords： tissue engineering     scaffolds     electrospinning     3D printing     molding techniques     conventional methods    

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Hierarchically Inverse Opal Porous Scaffolds from Droplet Microfluidics for Biomimetic 3D Cell Co-Culture Article

Changmin Shao, Yuxiao Liu, Junjie Chi, Fangfu Ye, Yuanjin Zhao

Engineering 2021, Volume 7, Issue 12,   Pages 1778-1785 doi: 10.1016/j.eng.2020.06.031

Abstract: However, existing scaffolds or microcarriers for 3D cell culture are often limited in size and show suboptimalThis work demonstrates that the resultant scaffolds ensure a sufficient supply of nutrients during cellThese hierarchically inverse opal scaffolds lay the foundation for 3D cell culture and even the construction

Keywords： Microfluidics     Inverse opal     Cell culture     Droplet     Biomaterial    

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Quality Monitoring of Porous Zein Scaffolds: A Novel Biomaterial

Yue Zhang, Wei-Ying Li, Run Lan, Jin-Ye Wang

Engineering 2017, Volume 3, Issue 1,   Pages 130-135 doi: 10.1016/J.ENG.2017.01.001

Abstract: range of 20–30 kGy, which suggested that γ-ray sterilization is suitable for porous zein scaffolds

Keywords： Zein     Amino acid analysis     SDS-PAGE     Gamma-ray sterilization     MTT assay     CCK-8 assay    

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Current progress on scaffolds of tissue engineering heart valves

DONG Nianguo, SHI Jiawei, CHEN Si, HONG Hao, HU Ping

Frontiers of Medicine 2008, Volume 2, Issue 3,   Pages 229-234 doi: 10.1007/s11684-008-0043-9

Abstract: And this article will briefly review the current research and progress on the scaffolds of TEHV, especially

Keywords： function     scaffold     promising     research     engineering    

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New branched benign compounds including double antibiotic scaffolds: synthesis, simulation and adsorption

Frontiers of Chemical Science and Engineering 2023, Volume 17, Issue 2,   Pages 167-182 doi: 10.1007/s11705-022-2199-2

Abstract: In this study, two novel environmental benign double antibiotic norfloxacin or ciprofloxacin scaffolds

Keywords： branched compounds     floxacin scaffold     mild steel     anticorrosion     environmentally benign    

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Cryo-copolymerization preparation of dextran-hyaluronate based supermacroporous cryogel scaffolds for

Dongjiao ZHOU, Shaochuan SHEN, Junxian YUN, Kejian YAO, Dong-Qiang LIN

Frontiers of Chemical Science and Engineering 2012, Volume 6, Issue 3,   Pages 339-347 doi: 10.1007/s11705-012-1209-1

Abstract: Dextran-hyaluronate (Dex-HA) based supermacroporous cryogel scaffolds for soft tissue engineering werewalls and grew inside the scaffold indicating the Dex-HA cryogel scaffold could be a promising porous biomaterial

Keywords： cryogel scaffold     tissue engineering     dextran     hyaluronate     3T3-L1 preadipocyte    

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Hemocompatible polyurethane/gelatin-heparin nanofibrous scaffolds formed by a bi-layer electrospinning

Heyun WANG, Yakai FENG, Marc BEHL, Andreas LENDLEIN, Haiyang ZHAO, Ruofang XIAO, Jian LU, Li ZHANG, Jintang GUO

Frontiers of Chemical Science and Engineering 2011, Volume 5, Issue 3,   Pages 392-400 doi: 10.1007/s11705-011-1202-0

Abstract: The tubular scaffolds (inner diameter 4 mm, length 3 cm) are composed of a polyurethane (PU) fibrousThe microstructure, fiber morphology and mechanical properties of the scaffolds were examined by meansThe PU/gelatin-heparin tubular scaffolds have a porous structure.The scaffolds achieved a breaking strength (3.7±0.13 MPa) and an elongation at break (110±8%) that areIn platelet adhesion tests the gelatin-heparin fibrous scaffolds showed a significant suppression of

Keywords： electrospinning     artificial blood vessels     scaffold     polyurethane     gelatin     nanofiber     hemocompatibility    

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Surface modification of biomaterials by photochemical immobilization and photograft polymerization to improve hemocompatibility

Yakai FENG, Haiyang ZHAO, Li ZHANG, Jintang GUO,

Frontiers of Chemical Science and Engineering 2010, Volume 4, Issue 3,   Pages 372-381 doi: 10.1007/s11705-010-0005-z

Abstract: Three approaches to modify biomaterial surfaces for improving the hemocompatibility, i.e., bioinert surfaces

Keywords： biomimetic amphiphilic     amphiphilic phosphorylcholine     endothelial     functional     biomaterial    

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Application of Biomaterials in Cardiac Repair and Regeneration Review

Zhi Cui,Baofeng Yang,Ren-Ke Li

Engineering 2016, Volume 2, Issue 1,   Pages 141-148 doi: 10.1016/J.ENG.2016.01.028

Abstract:

Cardiovascular disease is a leading cause of death throughout the world. The demand for new therapeutic interventions is increasing. Although pharmacological and surgical interventions dramatically improve the quality of life of cardiovascular disease patients, cheaper and less invasive approaches are always preferable. Biomaterials, both natural and synthetic, exhibit great potential in cardiac repair and regeneration, either as a carrier for drug delivery or as an extracellular matrix substitute scaffold. In this review, we discuss the current treatment options for several cardiovascular diseases, as well as types of biomaterials that have been investigated as potential therapeutic interventions for said diseases. We especially highlight investigations into the possible use of conductive polymers for correcting ischemic heart disease-induced conduction abnormalities, and the generation of biological pacemakers to improve the conduction pathway in heart block.

Keywords： Myocardial infarction     Heart regeneration     Biomaterial     Tissue engineering     Stem cell    

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Biocompatibility Pathways in Tissue-Engineering Templates Perspective

David F. Williams

Engineering 2018, Volume 4, Issue 2,   Pages 286-290 doi: 10.1016/j.eng.2018.03.007

Abstract: The specifications for these structures, which used to be described as scaffolds but are now more correctly

Keywords： Biomaterials     Scaffolds     Mechanotransduction     Inflammation     Topography    

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Microfluidics for Medical Additive Manufacturing Review

Jie Wang, Changmin Shao, Yuetong Wang, Lingyun Sun, Yuanjin Zhao

Engineering 2020, Volume 6, Issue 11,   Pages 1244-1257 doi: 10.1016/j.eng.2020.10.001

Abstract:

Additive manufacturing plays a vital role in the food, mechanical, pharmaceutical, and medical fields. Within these fields, medical additive manufacturing has led to especially obvious improvements in medical instruments, prostheses, implants, and so forth, based on the advantages of cost-effectiveness, customizability, and quick manufacturing. With the features of precise structural control, high throughput, and good component manipulation, microfluidic techniques present distinctive benefits in medical additive manufacturing and have been applied in the areas of drug discovery, tissue engineering, and organs on chips. Thus, a comprehensive review of microfluidic techniques for medical additive manufacturing is useful for scientists with various backgrounds. Herein, we review recent progress in the development of microfluidic techniques for medical additive manufacturing. We evaluate the distinctive benefits associated with microfluidic technologies for medical additive manufacturing with respect to the fabrication of droplet/fiber templates with different structures. Extensive applications of microfluidic techniques for medical additive manufacturing are emphasized, such as cell guidance, three-dimensional (3D) cell culture, tissue assembly, and cell-based therapy. Finally, we present challenges in and future perspectives on the development of microfluidics for medical additive manufacturing.

Keywords： Microfluidics     Biomaterial     Additive manufacturing     Droplet     Fiber    

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Rise of the Liquid Metal Science, Technology and Industry: Advancements and Opportunities

Liu Jing

Strategic Study of CAE 2020, Volume 22, Issue 5,   Pages 93-103 doi: 10.15302/J-SSCAE-2020.05.016

Abstract:

The room temperature liquid metal and its allied materials are a class of emerging functional matters with diverse species. Recently, with breakthrough discoveries made on liquid metals, tremendous exciting applications were raised and many new materials that had never been anticipated before were invented. As a result, the latest achievements on liquid metals were ascribed as the second revolution of human beings over the process of utilizing metals. This article briefly summarized typical advancements, fundamental sciences, and key technological and industrial areas thus initiated which include but are not limited to: chip cooling and energy utilization, printed electronics and 3D printing, biomedical materials, as well as smart soft machines. In addition, historic background to propose and establish “The China Liquid Metal Valley” and the basic strategy to mold a brand new industry of liquid metal were outlined. The core values to strengthen future research on liquid metal material genome engineering and thus build up corresponding databases were summarized. Overall, liquid metals are important frontiers for science, technology, and industry integrating both fundamental and practical issues together. Further continuous endeavors would lead to pivotal progress of human civilization and thus reshape social production and lifestyle. Its impact for both China and the world to explore next generation revolutionary science, technology, and industry will be huge.

Keywords： liquid metal     new material     disruptive technology     new industry     advanced cooling     printed electronics     biomaterial    

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Progress of three-dimensional macroporous bioactive glass for bone regeneration

Lijun JI, Yunfeng SI, Ailing LI, Wenjun WANG, Dong QIU, Aiping ZHU

Frontiers of Chemical Science and Engineering 2012, Volume 6, Issue 4,   Pages 470-483 doi: 10.1007/s11705-012-1217-1

Abstract: Bioactive glasses (BGs) are ideal materials for macroporous scaffolds due to their excellent osteoconductiveMacroporous scaffolds made from BGs are in high demand for bone regeneration because they can stimulatevascularized bone ingrowth and they enhance bonding between scaffolds and surrounding tissues.Engineering BG/biopolymers (BP) composites or hybrids may be a good way to prepare macroporous scaffoldsuse in load bearing applications, the mechanical properties of macroporous scaffolds are particularly

Keywords： bioactive glass     biopolymer     bone regeneration     macroporous scaffolds     tissue engineering    

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Title Author Date Type Operation

Sodium cellulose sulfate: A promising biomaterial used for microcarriers’ designing

Qing-Xi Wu, Yi-Xin Guan, Shan-Jing Yao

Journal Article

Combination of biomaterial transplantation and genetic enhancement of intrinsic growth capacities to

Bin Yu, Xiaosong Gu

Journal Article

Fabrication of scaffolds in tissue engineering: A review

Peng ZHAO, Haibing GU, Haoyang MI, Chengchen RAO, Jianzhong FU, Lih-sheng TURNG

Journal Article

Hierarchically Inverse Opal Porous Scaffolds from Droplet Microfluidics for Biomimetic 3D Cell Co-Culture

Changmin Shao, Yuxiao Liu, Junjie Chi, Fangfu Ye, Yuanjin Zhao

Journal Article

Quality Monitoring of Porous Zein Scaffolds: A Novel Biomaterial

Yue Zhang, Wei-Ying Li, Run Lan, Jin-Ye Wang

Journal Article

Current progress on scaffolds of tissue engineering heart valves

DONG Nianguo, SHI Jiawei, CHEN Si, HONG Hao, HU Ping

Journal Article

New branched benign compounds including double antibiotic scaffolds: synthesis, simulation and adsorption

Journal Article

Cryo-copolymerization preparation of dextran-hyaluronate based supermacroporous cryogel scaffolds for

Dongjiao ZHOU, Shaochuan SHEN, Junxian YUN, Kejian YAO, Dong-Qiang LIN

Journal Article

Hemocompatible polyurethane/gelatin-heparin nanofibrous scaffolds formed by a bi-layer electrospinning

Heyun WANG, Yakai FENG, Marc BEHL, Andreas LENDLEIN, Haiyang ZHAO, Ruofang XIAO, Jian LU, Li ZHANG, Jintang GUO

Journal Article

Surface modification of biomaterials by photochemical immobilization and photograft polymerization to improve hemocompatibility

Yakai FENG, Haiyang ZHAO, Li ZHANG, Jintang GUO,

Journal Article

Application of Biomaterials in Cardiac Repair and Regeneration

Zhi Cui,Baofeng Yang,Ren-Ke Li

Journal Article

Biocompatibility Pathways in Tissue-Engineering Templates

David F. Williams

Journal Article

Microfluidics for Medical Additive Manufacturing

Jie Wang, Changmin Shao, Yuetong Wang, Lingyun Sun, Yuanjin Zhao

Journal Article

Rise of the Liquid Metal Science, Technology and Industry: Advancements and Opportunities

Liu Jing

Journal Article

Progress of three-dimensional macroporous bioactive glass for bone regeneration

Lijun JI, Yunfeng SI, Ailing LI, Wenjun WANG, Dong QIU, Aiping ZHU

Journal Article